Disease Pathways
We will cure ALS when we better understand how and why it happens. Project A.L.S.™ is working to identify the underlying causes and pathways of ALS.
Project A.L.S.™ have uncovered important clues recently: the relationship between motor neurons and support cells called astrocytes turns nasty in ALS…the gene Foxp1 is a switch for a family of genes that dictate synaptic specificity…interneurons, cells that have not been considered to play a part in ALS, may serve an important role.
The main strategy in understanding ALS–and therapeutic approaches-is to support basic studies in neuroscience, and apply that knowledge to ALS. Understanding the normal brain guides our approaches to making a sick brain better.
