Disease Pathways
We will cure ALS when we better understand how and why it happens. Project A.L.S.™ is working to identify the underlying causes and pathways of ALS.
Project A.L.S.™ have uncovered important clues recently: the relationship between motor neurons and support cells called astrocytes turns nasty in ALS…the gene Foxp1 is a switch for a family of genes that dictate synaptic specificity…interneurons, cells that have not been considered to play a part in ALS, may serve an important role.
The main strategy in understanding ALS–and therapeutic approaches-is to support basic studies in neuroscience, and apply that knowledge to ALS. Understanding the normal brain guides our approaches to making a sick brain better.
The mission of Project A.L.S.™ is to recruit the world’s best research scientists and clinicians to work together toward an understanding of and the first effective treatments for ALS (amyotrophic lateral sclerosis), also known as Lou Gehrig’s disease.
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